Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445028 | 0.88 | EGFR (0.75) | EGFRKCNH2 | |
| Hydrochloric Acid SCHEMBL4447512 | 0.87 | EGFR (0.73) | EGFRKCNH2 | |
| SCHEMBL4443018 | 0.87 | EGFR (0.73) | EGFRKCNH2 | |
| SCHEMBL4443366 | 0.86 | EGFR (0.70) | EGFRKCNH2 | |
| SCHEMBL10100955 | 0.86 | KDR (0.75) | EGFRKCNH2 | |
| Hydrochloric Acid SCHEMBL6008951 | 0.85 | EGFR (0.71) | EGFRKCNH2 | |
| SCHEMBL6008954 | 0.85 | EGFR (0.71) | EGFRKCNH2 | |
| SCHEMBL4443069 | 0.85 | EGFR (0.63) | EGFRKCNH2 | |
| SCHEMBL19227377 | 0.84 | EGFR (0.67) | EGFRKCNH2 | |
| SCHEMBL4445126 | 0.84 | EGFR (0.67) | EGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713781-A1 | QUINAZOLINE DERIVATIVES | AstraZeneca AB (SE) | 2006-10-25 | — | — | EP | disclosed |
| EP-1664030-A1 | QUINAZOLINE DERIVATIVES | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005075439-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | disclosed |
| WO-2005026156-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | disclosed |