Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451676 | 0.90 | ACE (0.56) | ACEMME | |
| SCHEMBL5695616 | 0.89 | ACE (0.57) | ACE | |
| SCHEMBL5695581 | 0.89 | ACE (0.69) | ACE | |
| SCHEMBL5695634 | 0.89 | ACE (0.69) | ACE | |
| SCHEMBL5695664 | 0.89 | ACE (0.69) | ACE | |
| SCHEMBL5695741 | 0.86 | ACE (0.74) | ACE | |
| SCHEMBL8076791 | 0.86 | ACE (0.74) | ACE | |
| SCHEMBL5695595 | 0.81 | ACE (0.72) | ACE | |
| SCHEMBL5695725 | 0.81 | ACE (0.69) | ACE | |
| SCHEMBL5695656 | 0.80 | ACE (0.58) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947502-B1 | NOVEL SULFUR-CONTAINING AMINO ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-6046235-A | SULFUR-CONTAINING AMINO ACID DERIVATIVES WHICH HAVE INHIBITORY EFFECTS ON LEUKOTRIENE A4 HYDROLASE AND USEFUL AS THERAPEUTICAL AGENTS FOR INFLAMMATORY DISEASES SUCH AS RHEUMATISM, PSORIASIS, GOUT, CYSTIC FIBROSIS AND BOWL DISEASES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0947502-A1 | NOVEL SULFUR-CONTAINING AMINO ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |