Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 18/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074628 | 0.89 | ACE (1.00) | ACE | |
| SCHEMBL5695709 | 0.89 | ACE (1.00) | ACE | |
| SCHEMBL5695576 | 0.89 | ACE (1.00) | ACE | |
| SCHEMBL5695594 | 0.89 | ACE (1.00) | ACE | |
| SCHEMBL5695612 | 0.89 | ACE (1.00) | ACE | |
| SCHEMBL5695578 | 0.88 | ACE (1.00) | ACE | |
| SCHEMBL5696367 | 0.88 | ACE (1.00) | ACE | |
| SCHEMBL5696359 | 0.88 | ACE (1.00) | ACE | |
| SCHEMBL5695642 | 0.88 | ACE (1.00) | ACE | |
| SCHEMBL5695742 | 0.88 | ACE (1.00) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947502-B1 | NOVEL SULFUR-CONTAINING AMINO ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-06-21 | — | — | EP | claimed |
| US-6046235-A | SULFUR-CONTAINING AMINO ACID DERIVATIVES WHICH HAVE INHIBITORY EFFECTS ON LEUKOTRIENE A4 HYDROLASE AND USEFUL AS THERAPEUTICAL AGENTS FOR INFLAMMATORY DISEASES SUCH AS RHEUMATISM, PSORIASIS, GOUT, CYSTIC FIBROSIS AND BOWL DISEASES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-04-04 | — | — | US | claimed |
| EP-0947502-A1 | NOVEL SULFUR-CONTAINING AMINO ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | claimed |
| EP-0947502-B1 | NOVEL SULFUR-CONTAINING AMINO ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-6046235-A | SULFUR-CONTAINING AMINO ACID DERIVATIVES WHICH HAVE INHIBITORY EFFECTS ON LEUKOTRIENE A4 HYDROLASE AND USEFUL AS THERAPEUTICAL AGENTS FOR INFLAMMATORY DISEASES SUCH AS RHEUMATISM, PSORIASIS, GOUT, CYSTIC FIBROSIS AND BOWL DISEASES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0947502-A1 | NOVEL SULFUR-CONTAINING AMINO ACID DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |