Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5696185

CCC(C)C(N)C(=O)N1CCC[C@H]1C#N.O=C(O)C(F)(F)F

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 18/20 0.84
DPP8 Q6V1X1 10/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5203128 1.00 DPP4 (0.84) DPP4DPP8
Trifluoroacetic Acid SCHEMBL5203132 1.00 DPP4 (0.84) DPP4DPP8
SCHEMBL6238524 0.92 DPP4 (1.00) DPP4DPP8
SCHEMBL5647937 0.92 DPP4 (1.00) DPP4DPP8
SCHEMBL6238520 0.92 DPP4 (1.00) DPP4DPP8
SCHEMBL5647935 0.92 DPP4 (1.00) DPP4DPP8
Hydrochloric Acid SCHEMBL5652236 0.90 DPP4 (0.97) DPP4DPP8
Hydrochloric Acid SCHEMBL5652234 0.90 DPP4 (0.97) DPP4DPP8
Hydrochloric Acid SCHEMBL3601691 0.90 DPP4 (0.97) DPP4DPP8
Hydrochloric Acid SCHEMBL5049190 0.90 DPP4 (0.97) DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7115650-B1 Compositions for improving fertility FERRING BV (NL) 2006-10-03 US disclosed
EP-1162969-B1 use of dipeptidyl peptidase IV inhibitors fOR IMPROVING FERTILITY FERRING BV (NL) 2006-06-07 EP disclosed
EP-1171121-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING DIPEPTIDYLPEPTIDASE IV INHIBITORS FOR THE PROMOTION OF GROWTH FERRING BV (NL) 2005-06-15 EP disclosed
US-6521644-B1 Treatment subnormal development or dwarfism; administering dipeptidyl peptidase IV inhibitor FERRING BV (NL) 2003-02-18 US disclosed
EP-1162969-A2 COMPOSITIONS FOR IMPROVING FERTILITY Ferring BV (NL) 2001-12-19 EP disclosed
WO-2000056296-A2 COMPOSITIONS FOR IMPROVING FERTILITY FERRING BV (NL) 2000-09-28 WO disclosed