⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598372 | 0.78 | TSHR (0.32) | — | |
| SCHEMBL20609984 | 0.76 | — | — | |
| SCHEMBL6278524 | 0.75 | — | — | |
| SCHEMBL4468978 | 0.74 | CYP2D6 (0.45) | — | |
| SCHEMBL21925338 | 0.74 | — | — | |
| SCHEMBL4234783 | 0.74 | TSHR (0.32) | — | |
| SCHEMBL1971314 | 0.74 | — | — | |
| SCHEMBL12985130 | 0.74 | — | — | |
| SCHEMBL8152015 | 0.74 | — | — | |
| SCHEMBL18185197 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939639-B1 | METHODS AND COMPOSITIONS FOR REDUCING OR ELIMINATING POST-SURGICAL ADHESION FORMATION | LIFE MEDICAL SCIENCES INC (US) | 2006-06-21 | — | — | EP | claimed |
| US-6080833-A | BIS(HYDROXYALKOXYLATED) 1,1'-SPIROBIINDAN POLYCARBONATES AND POLYESTERS POLYMERS AND CURABLE COMPOUNDS SUCH AS BIS(ACRYLATED ALKOXY)SPIROBIINDANS; ALSO POLYAMIDES AND POLYIMIDES CONTAINING SPIROBIINDAN GROUPS | MITSUI CHEMICALS, INC. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0822545-A2 | Optical component and spirobiindan polymer therefor | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1998-02-04 | — | — | EP | disclosed |