Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 20/20 | 0.71 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.71 |
| ▸ | OXTR | P30559 | 7/20 | 0.71 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.67 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464433 | 0.93 | AVPR1B (0.81) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL1464434 | 0.93 | AVPR1B (0.81) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| Dimethylamine SCHEMBL5696375 | 0.90 | AVPR1B (0.69) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL5695764 | 0.87 | AVPR1B (0.75) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL1465204 | 0.86 | AVPR1B (0.79) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL1465203 | 0.86 | AVPR1B (0.79) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL1465080 | 0.85 | AVPR1B (0.93) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL1465081 | 0.85 | AVPR1B (0.93) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL1464480 | 0.84 | AVPR1B (0.85) | AVPR1BAVPR1AOXTRAVPR2GPR65 | |
| SCHEMBL1465239 | 0.83 | AVPR1B (1.00) | AVPR1BAVPR1AOXTRAVPR2GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667993-A1 | HETEROARYL-SUBSTITUTED 1,3-DIHYDROINDOL-2-ONE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | Abbott GmbH & Co. KG (DE) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030755-A1 | HETEROARYL-SUBSTITUTED 1,3-DIHYDROINDOL-2-ONE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | ABBOTT GMBH & CO. KG (DE) | 2005-04-07 | — | — | WO | disclosed |