Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 19/20 | 0.45 |
| ▸ | EGFR | P00533 | 10/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697288 | 0.90 | ERBB2 (0.51) | ERBB2EGFRKCNH2 | |
| SCHEMBL4484121 | 0.79 | ERBB2 (0.49) | ERBB2EGFRKCNH2 | |
| SCHEMBL4391656 | 0.78 | ERBB2 (0.67) | ERBB2EGFRKCNH2 | |
| SCHEMBL5696820 | 0.78 | ERBB2 (0.67) | ERBB2EGFRKCNH2 | |
| SCHEMBL4387759 | 0.78 | ERBB2 (0.67) | ERBB2EGFRKCNH2 | |
| SCHEMBL4396280 | 0.78 | ERBB2 (0.64) | ERBB2EGFRKCNH2 | |
| SCHEMBL5696875 | 0.78 | ERBB2 (0.64) | ERBB2EGFRKCNH2 | |
| SCHEMBL4481980 | 0.77 | ERBB2 (0.46) | ERBB2EGFRKCNH2 | |
| SCHEMBL4476879 | 0.77 | ERBB2 (0.66) | ERBB2EGFRKCNH2 | |
| SCHEMBL4480016 | 0.77 | EGFR (0.48) | ERBB2EGFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664029-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026152-A1 | QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | disclosed |