Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 16/20 | 0.73 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | NMBR | P28336 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697888 | 0.91 | KCNA5 (0.67) | KCNA5KCNK3KCNA3NMBR | |
| SCHEMBL5697860 | 0.88 | KCNA5 (0.56) | KCNA5 | |
| SCHEMBL5697904 | 0.87 | KCNA5 (0.56) | KCNA5KCNK3KCNA3 | |
| SCHEMBL5697870 | 0.87 | KCNA5 (0.74) | KCNA5 | |
| SCHEMBL5697828 | 0.87 | KCNA5 (0.69) | KCNA5 | |
| SCHEMBL5697902 | 0.84 | KCNA5 (0.54) | KCNA5 | |
| SCHEMBL2206577 | 0.84 | KCNA5 (1.00) | KCNA5KCNK3KCNA3 | |
| SCHEMBL5697892 | 0.84 | KCNA5 (0.69) | KCNA5 | |
| SCHEMBL5697830 | 0.83 | KCNA5 (0.57) | KCNA5KCNK3KCNA3 | |
| SCHEMBL5697836 | 0.82 | KCNA5 (0.69) | KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1222163-B1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-07-12 | — | — | EP | disclosed |
| EP-1222163-A1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | Aventis Pharma Deutschland GmbH (DE) | 2002-07-17 | — | — | EP | disclosed |
| WO-2001025189-A1 | 2'-SUBSTITUTED 1,1'-BIPHENYL-2-CARBONAMIDES, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-04-12 | — | — | WO | disclosed |