Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA4 | P22748 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL8133738 | 0.97 | CA1 (0.56) | CA1CA4TP53FAHD1CA2 | |
| L-Lactic Acid SCHEMBL915750 | 0.93 | CA1 (0.53) | CA1CA4TP53CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL1321472 | 0.93 | CA1 (0.60) | CA1CA4TP53FAHD1CA2 | |
| L-Lactic Acid SCHEMBL28475100 | 0.93 | CA1 (0.53) | CA1CA4TP53CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL5921228 | 0.93 | CA1 (0.53) | CA1CA4TP53CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL1741442 | 0.93 | CA1 (0.53) | CA1CA4TP53CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL1168923 | 0.93 | CA1 (0.60) | CA1CA4TP53FAHD1CA2 | |
| L-Lactic Acid SCHEMBL1741444 | 0.93 | CA1 (0.53) | CA1CA4TP53CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL915748 | 0.93 | CA1 (0.53) | CA1CA4TP53CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL37615 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1659871-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE EFFICIENCY OF PRESERVATIVES IN FOODS | RAD Natural Technologies Ltd. (IL) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005011390-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE EFFICIENCY OF PRESERVATIVES IN FOODS | RAD NATURAL TECHNOLOGIES LTD. (IL) | 2005-02-10 | — | — | WO | disclosed |