Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.52 |
| ▸ | F2 | P00734 | 14/20 | 0.52 |
| ▸ | F9 | P00740 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PROC | P04070 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698180 | 0.91 | F10 (0.47) | F10F2F9PLAUPROC | |
| SCHEMBL6392282 | 0.87 | F10 (0.69) | F10F2F9PLAUPROC | |
| SCHEMBL5698152 | 0.84 | F10 (0.52) | F10F2F9PLAUPROC | |
| SCHEMBL5698220 | 0.82 | F10 (0.52) | F10F2CTRB1 | |
| SCHEMBL5698171 | 0.82 | F10 (0.46) | F10F2F9 | |
| SCHEMBL5698239 | 0.80 | F10 (0.52) | F10F2CTRB1 | |
| SCHEMBL6390506 | 0.78 | F10 (0.61) | F10F2F9PLAUPROC | |
| SCHEMBL5698190 | 0.73 | F10 (0.46) | F10F2F9 | |
| SCHEMBL5698167 | 0.72 | F10 (0.44) | F10F2F9 | |
| SCHEMBL5698177 | 0.72 | KLKB1 (0.40) | F10F2F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679073-A1 | 2-(PHENYL)-2H-PYRAZOLE-3-CARBOXYLIC ACID-N-4-(IMINO-HETEROCYCLYL)-PHENYL-AMIDE DERIVATIVES AND RELATES COMPOUNDS FOR USE AS INHIBITORS OF THE COAGULATION FACTORS XA AND/OR VIIA FOR TREATING THROMBOSES | MERCK PATENT GmbH (DE) | 2006-07-12 | — | — | EP | claimed |
| EP-1679073-A1 | 2-(PHENYL)-2H-PYRAZOLE-3-CARBOXYLIC ACID-N-4-(IMINO-HETEROCYCLYL)-PHENYL-AMIDE DERIVATIVES AND RELATES COMPOUNDS FOR USE AS INHIBITORS OF THE COAGULATION FACTORS XA AND/OR VIIA FOR TREATING THROMBOSES | MERCK PATENT GmbH (DE) | 2006-07-12 | — | — | EP | disclosed |