Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5698235 | 0.89 | GRM5 (1.00) | GRM5 | |
| SCHEMBL8285926 | 0.87 | GRM5 (0.78) | GRM5 | |
| SCHEMBL8286828 | 0.85 | GRM5 (0.81) | GRM5 | |
| SCHEMBL5698562 | 0.85 | GRM5 (0.74) | GRM5 | |
| SCHEMBL8286830 | 0.85 | GRM5 (1.00) | GRM5 | |
| SCHEMBL5698309 | 0.84 | GRM5 (0.72) | GRM5 | |
| SCHEMBL5698508 | 0.83 | GRM5 (0.72) | GRM5 | |
| SCHEMBL8286829 | 0.83 | GRM5 (0.76) | GRM5 | |
| SCHEMBL5698326 | 0.82 | GRM5 (0.70) | GRM5 | |
| SCHEMBL5698315 | 0.82 | GRM5 (1.00) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677788-A1 | ALKYNES III | AstraZeneca AB (SE) | 2006-07-12 | — | — | EP | claimed |
| WO-2005044265-A1 | ALKYNES III | ASTRAZENECA AB (SE) | 2005-05-19 | — | — | WO | claimed |
| WO-2005044265-A1 | ALKYNES III | ASTRAZENECA AB (SE) | 2005-05-19 | — | — | WO | disclosed |