⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777377 | 0.84 | F2 (0.42) | — | |
| SCHEMBL28199154 | 0.79 | — | — | |
| SCHEMBL27389773 | 0.77 | — | — | |
| SCHEMBL27984900 | 0.77 | — | — | |
| SCHEMBL28201985 | 0.77 | — | — | |
| SCHEMBL3612315 | 0.77 | — | — | |
| SCHEMBL15954726 | 0.77 | — | — | |
| SCHEMBL27714465 | 0.77 | — | — | |
| SCHEMBL1382152 | 0.77 | — | — | |
| SCHEMBL28299258 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105916499-B | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2020-02-18 | — | — | CN | disclosed |
| CN-107107433-B | Method for the gel reduction in polyolefin | 尤尼威蒂恩技术有限责任公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-107206655-B | Method for controlling polymer chain scission | 尤尼威蒂恩技术有限责任公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-105814047-B | Fused tricyclic imdazole derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-10-19 | — | — | CN | disclosed |
| CN-108341943-A | A kind of hydridization dynamic aggregation object and its application | 翁秋梅 | 2018-07-31 | — | — | CN | disclosed |
| CN-104619709-B | Imidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105814055-A | Fused imidazole and pyrazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105814047-A | Fused tricyclic benzimidazoles derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105814065-A | Imidazothiazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-104540859-A | Enhanced polymer melt flow ratio by supplying a supported catalyst saturated with a selected liquid reagent | UNIVATION TECH LLC | 2015-04-22 | — | — | CN | disclosed |
| CN-102361866-B | Process for preparing propionic acid derivatives | HOFFMANN LA ROCHE | 2015-03-25 | — | — | CN | disclosed |
| CN-104125962-A | Tetracyclic anthraquinone derivatives | TIANJIN HEMAY BIO TECH CO LTD | 2014-10-29 | — | — | CN | disclosed |
| EP-1682143-A2 | COMBINATIONS COMPRISING AN HSP90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | Pharmacia Corporation (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044194-A2 | TREATMENT OR PREVENTION OF NEOPLASIA BY USE OF AN Hsp90 INHIBITOR | PHARMACIA CORPORATION (US) | 2005-05-19 | — | — | WO | disclosed |
| WO-2005041879-A2 | COMBINATIONS COMPRISING AN Hsp90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA | PHARMACIA CORPORATION (US) | 2005-05-12 | — | — | WO | disclosed |
| WO-2001027096-A9 | AMINOMETHYL-(HETERO)ARYL DERIVATIVES AND THEIR USE AS TRYPTASE INHIBITORS | PROTHERICS MOLECULAR DESIGN LT (GB) | 2001-07-12 | — | — | WO | disclosed |
| US-4479906-A | BLACK LEATHER DYE | BASF AKTIENGESELLSCHAFT (DE) | 1984-10-30 | — | — | US | disclosed |
| US-4235773-A | Trisazo dyestuffs containing a naphtholamino sulfonic acid component and a phenylcarbonylamino-phenyl component | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |