Tyrosine

Tyrosine

SCHEMBL5699043

N[C@@H](Cc1ccc(O)cc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.89

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.89
PTGS1 P23219 2/20 0.81
ALPI P09923 1/20 0.81
PKM P14618 1/20 0.81
XIAP P98170 1/20 0.81
GRIA2 P42262 1/20 0.59
SLC1A3 P43003 2/20 0.59
SLC1A2 P43004 2/20 0.59
SLC1A1 P43005 2/20 0.59
KDM4E B2RXH2 1/20 0.59
USP2 O75604 1/20 0.59
EGFR P00533 1/20 0.59
LCK P06239 1/20 0.59
FYN P06241 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
ALOX15 P16050 1/20 0.59
HTR2A P28223 1/20 0.59
PTGS2 P35354 1/20 0.59
RECQL P46063 1/20 0.59
HIF1A Q16665 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL5699039 1.00 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL27641183 1.00 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL18222727 1.00 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1003558 1.00 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28244030 1.00 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL133206 1.00 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL4258460 0.98 SLC7A5 (0.86) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28900255 0.96 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1908049 0.96 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1908048 0.96 SLC7A5 (0.89) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230152235-A1 IMPROVED BIOMOLECULE DETECTION USING SURFACE-ENHANCED RAMAN SPECTROSCOPY NOSTICS B.V. (NL) 2023-05-18 US disclosed
EP-1689249-A1 DIETARY NON-ESSENTIAL AMINO ACID TYROSINE REGULATES THE BODY WEIGHT OF ANIMALS THROUGH REGULATING THE ANIMAL APPETITE OR FOOD INTAKE Hill's Pet Nutrition Inc. (US) 2006-08-16 EP disclosed
WO-2005055738-A1 DIETARY NON-ESSENTIAL AMINO ACID TYROSINE REGULATES THE BODY WEIGHT OF ANIMALS THROUGH REGULATING THE ANIMAL APPETITE OR FOOD INTAKE HILL'S PET NUTRITION, INC. (US) 2005-06-23 WO disclosed