Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.57 |
| ▸ | PPARG | P37231 | 13/20 | 0.57 |
| ▸ | PPARA | Q07869 | 13/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520819 | 0.91 | PPARD (0.45) | PPARDPPARGPPARAFFAR1THRB | |
| SCHEMBL4516544 | 0.89 | PPARD (0.69) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL4517393 | 0.88 | PPARD (0.44) | PPARDPPARGPPARAFFAR1CYP1A2 | |
| SCHEMBL4512818 | 0.87 | PPARD (0.67) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL4511257 | 0.84 | PPARG (0.56) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL4516190 | 0.83 | PPARD (0.70) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL4526243 | 0.83 | PPARD (0.70) | PPARDPPARGPPARAFFAR1FFAR4 | |
| SCHEMBL4517797 | 0.82 | PPARD (0.44) | PPARDPPARGPPARAFFAR1CYP1A2 | |
| SCHEMBL4511611 | 0.81 | PPARG (0.43) | PPARDPPARGPPARAFFAR1CYP1A2 | |
| SCHEMBL4526047 | 0.81 | PPARG (0.42) | PPARDPPARGPPARAFFAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675814-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005037763-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |