⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL15065453 | 0.94 | TSHR (0.36) | — | |
| Butane SCHEMBL22491 | 0.93 | — | — | |
| Butane SCHEMBL3125984 | 0.93 | TSHR (0.44) | — | |
| Butane SCHEMBL5859491 | 0.93 | TSHR (0.44) | — | |
| Butane SCHEMBL421381 | 0.93 | — | — | |
| Butane SCHEMBL13278079 | 0.93 | TSHR (0.44) | — | |
| Butane SCHEMBL110819 | 0.93 | — | — | |
| Butane SCHEMBL9015750 | 0.93 | TSHR (0.44) | — | |
| Butane SCHEMBL30942544 | 0.93 | — | — | |
| Butane SCHEMBL11217023 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037673-B1 | CHARGED LIPIDS AND USES FOR THE SAME | IMARX PHARMACEUTICAL CORP (US) | 2006-08-23 | — | — | EP | claimed |
| US-6808720-B2 | DRUG DELIVERY; CONTRAST FOR MEDICAL DIAGNOSIS | IMARX THERAPEUTICS, INC. | 2004-10-26 | — | — | US | claimed |
| US-20030054027-A1 | Charged lipids and uses for the same | IMARX THERAPEUTICS, INC. | 2003-03-20 | — | — | US | claimed |
| US-6403056-B1 | ADMINISTERING AGENT; APPLYING ULTRASONIC FREQUENCY | IMARX THERAPEUTICS, INC. | 2002-06-11 | — | — | US | claimed |
| EP-1037673-A4 | CHARGED LIPIDS AND USES FOR THE SAME | IMARX PHARMACEUTICAL CORP (US) | 2002-05-02 | — | — | EP | claimed |
| EP-1037673-A1 | CHARGED LIPIDS AND USES FOR THE SAME | IMARX PHARMACEUTICAL CORP. (US) | 2000-09-27 | — | — | EP | claimed |
| WO-1998042383-A1 | CHARGED LIPIDS AND USES FOR THE SAME | IMARX PHARMACEUTICAL CORP. (US) | 1998-10-01 | — | — | WO | claimed |
| US-20230220019-A1 | CHEMICALLY-STABILIZED ALLOSTERIC MODULATORS OF LEUCINERICH REPEAT KINASE 2 (LRRK2) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2023-07-13 | — | — | US | disclosed |
| EP-4110357-A1 | CHEMICALLY-STABILIZED ALLOSTERIC MODULATORS OF LEUCINE-RICH REPEAT KINASE 2 (LRRK2) | University of Georgia Research Foundation, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |
| CN-108603173-A | The method of T Lymphocyte expansions | 剑桥企业有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-105873944-A | Pro-angiogenic peptides and peptide conjugates | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-105579464-A | Peptides capable of reactivating p53 mutants | YEDA RES & DEV | 2016-05-11 | — | — | CN | disclosed |
| CN-101646402-A | Porous, non-degradable implants made by powder molding | CINV AG DE | 2010-02-10 | — | — | CN | disclosed |