Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699357 | 1.00 | ADRB3 (0.42) | ADRB3PPARDPPARGNR3C1PGR | |
| SCHEMBL4811222 | 0.93 | ADRB3 (0.46) | ADRB3PPARDPPARGNR3C1PGR | |
| SCHEMBL4811239 | 0.93 | ADRB3 (0.46) | ADRB3PPARDPPARGNR3C1PGR | |
| SCHEMBL4811684 | 0.93 | MEN1 (0.39) | ADRB3PPARDPPARGNR3C1PGR | |
| SCHEMBL4811657 | 0.93 | MEN1 (0.39) | ADRB3PPARDPPARGNR3C1PGR | |
| SCHEMBL5699460 | 0.90 | FFAR1 (0.47) | ADRB3PPARDPPARGPPARAFFAR1 | |
| SCHEMBL5699461 | 0.90 | FFAR1 (0.47) | ADRB3PPARDPPARGPPARAFFAR1 | |
| SCHEMBL4808571 | 0.89 | PPARG (0.43) | ADRB3PPARGPPARA | |
| SCHEMBL4815151 | 0.89 | ADRB3 (0.39) | ADRB3PPARGADRB1PPARAADAMTS4 | |
| SCHEMBL4808561 | 0.89 | PPARG (0.43) | ADRB3PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679304-A1 | AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |