Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810264 | 1.00 | ADRB3 (0.47) | ADRB3ADAMTS4MMP13ADRB1MAPT | |
| SCHEMBL4810262 | 1.00 | ADRB3 (0.47) | ADRB3ADAMTS4MMP13ADRB1MAPT | |
| SCHEMBL4809407 | 0.94 | ADRB3 (0.46) | ADRB3ADAMTS4MMP13ADRB1RAB9A | |
| SCHEMBL4809396 | 0.94 | ADRB3 (0.46) | ADRB3ADAMTS4MMP13ADRB1RAB9A | |
| SCHEMBL4817704 | 0.93 | ADRB3 (0.51) | ADRB3ADAMTS4MMP13ADRB1RAB9A | |
| SCHEMBL4811239 | 0.90 | ADRB3 (0.46) | ADRB3ADAMTS4MMP13ADRB1RAB9A | |
| SCHEMBL4811222 | 0.90 | ADRB3 (0.46) | ADRB3ADAMTS4MMP13ADRB1RAB9A | |
| SCHEMBL4811685 | 0.88 | ADRB3 (0.40) | ADRB3ADRA1DADRA1AADRA1B | |
| SCHEMBL4811697 | 0.88 | ADRB3 (0.40) | ADRB3ADRA1DADRA1AADRA1B | |
| SCHEMBL4818523 | 0.87 | ADRB3 (0.52) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679304-A1 | AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |