Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122330 | 0.79 | TDP1 (0.39) | ALDH1A1TDP1TSHR | |
| SCHEMBL14930532 | 0.77 | TP53 (0.38) | TP53SLC7A5 | |
| Acetic Acid SCHEMBL23797687 | 0.75 | FFAR3 (0.64) | FFAR3LCKFYNTP53SLC7A5 | |
| Hydrochloric Acid SCHEMBL8779799 | 0.75 | TDP1 (0.36) | ALDH1A1TDP1TSHR | |
| Acetic Acid SCHEMBL1114492 | 0.73 | TDP1 (0.57) | FFAR3LCKFYNTP53CYP2D6 | |
| Acetic Acid SCHEMBL29173803 | 0.73 | TDP1 (0.57) | FFAR3LCKFYNTP53CYP2D6 | |
| Acetic Acid SCHEMBL28696323 | 0.71 | FFAR3 (0.70) | FFAR3LCKFYNTP53SLC7A5 | |
| Acetic Acid SCHEMBL29169948 | 0.71 | TDP1 (0.53) | FFAR3LCKFYNTP53CYP2D6 | |
| SCHEMBL12295867 | 0.69 | — | — | |
| Acetic Acid SCHEMBL18528147 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060204985-A1 | Method of hybridizing genes | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2006-09-14 | — | — | US | claimed |
| EP-1688505-A2 | Method of hybridizing nucleic acids | Samsung Electronics Co., Ltd. (KR) | 2006-08-09 | — | — | EP | claimed |
| US-20060204985-A1 | Method of hybridizing genes | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2006-09-14 | — | — | US | disclosed |
| EP-1688505-A2 | Method of hybridizing nucleic acids | Samsung Electronics Co., Ltd. (KR) | 2006-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060204985-A1 | Method of hybridizing genes | RIOX2, F13A1, MRPL21 | FFAR3 2541/4885LCK 4824/4885FYN 4837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.