Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 18/20 | 0.65 |
| ▸ | RARB | P10826 | 12/20 | 0.65 |
| ▸ | RARA | P10276 | 10/20 | 0.65 |
| ▸ | RXRA | P19793 | 4/20 | 0.57 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5845973 | 0.80 | RARG (0.69) | RARGRARBRARARXRA | |
| SCHEMBL5846100 | 0.79 | RARG (1.00) | RARGRARBRARARXRA | |
| SCHEMBL957014 | 0.79 | RARG (0.83) | RARGRARBRARARXRA | |
| SCHEMBL953791 | 0.79 | RARG (0.75) | RARGRARBRARARXRA | |
| SCHEMBL5699602 | 0.79 | RARG (0.72) | RARGRARBRARARXRA | |
| SCHEMBL5699625 | 0.79 | RARG (0.49) | RARGRARBRARARXRA | |
| SCHEMBL955323 | 0.79 | RARG (0.83) | RARGRARBRARARXRA | |
| SCHEMBL344900 | 0.78 | RARG (1.00) | RARGRARBRARARXRA | |
| SCHEMBL10002005 | 0.78 | RARG (0.92) | RARGRARBRARARXRA | |
| SCHEMBL5845874 | 0.78 | RARG (0.77) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692093-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development, S.N.C. (FR) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056516-A1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-06-23 | — | — | WO | disclosed |