Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021448 | 0.94 | KCNH2 (0.50) | KCNH2SLC6A2HRH1HRH3CHRM2 | |
| SCHEMBL9021745 | 0.93 | KCNH2 (0.49) | KCNH2SLC6A2HRH1HRH3CHRM2 | |
| SCHEMBL9021231 | 0.93 | KCNH2 (0.49) | KCNH2SLC6A2HRH1HRH3CHRM2 | |
| SCHEMBL9021167 | 0.93 | KCNH2 (0.49) | KCNH2SLC6A2HRH1HRH3CHRM2 | |
| SCHEMBL9154990 | 0.92 | KCNH2 (0.55) | KCNH2SLC6A2HRH1HRH3CHRM2 | |
| SCHEMBL9021407 | 0.91 | KCNH2 (0.54) | KCNH2SLC6A2HRH1HRH3CHRM2 | |
| SCHEMBL9249000 | 0.90 | SLC6A2 (0.64) | KCNH2SLC6A2HRH1HRH3CHRM2 | |
| SCHEMBL9021186 | 0.89 | KCNH2 (0.53) | KCNH2SLC6A2HRH1HRH3CHRM2 | |
| SCHEMBL9021280 | 0.89 | KCNH2 (0.53) | KCNH2SLC6A2HRH1HRH3CHRM2 | |
| SCHEMBL9021254 | 0.88 | TAAR1 (0.45) | KCNH2SLC6A2HRH1HRH3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024084379-A1 | A NOVEL PROCESS FOR THE PREPARATION OF AMORPHOUS SOLID DISPERSION OF 1-{3-[3-(4-CHLOROPHENYL) PROPOXY] PROPYL} PIPERIDINE, HYDROCHLORIDE WITH HYDROXYPROPYL BETA-CYCLODEXTRIN (HPβCD) | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD (IN) | 2024-04-25 | — | — | WO | disclosed |
| EP-1690858-A1 | Monohydrochloride salt of 1-¬3-¬3-(4-chlorophenyl)propoxy|propyl|-piperidine | FERRER INTERNACIONAL, S.A. (ES) | 2006-08-16 | — | — | EP | disclosed |
| EP-0500853-B1 | PHENYLETHANOLAMINES, DRUGS CONTAINING THESE COMPOUNDS, AND A METHOD OF PREPARING THEM | THOMAE GMBH DR K (DE) | 1996-12-27 | — | — | EP | disclosed |
| US-5393774-A | Antispasmodic agents | PIEPER HELMUT (DE) | 1995-02-28 | — | — | US | disclosed |