Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 18/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.55 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700865 | 1.00 | ITGB1 (0.55) | ITGB1ITGA4ITGB7RORCHTT | |
| SCHEMBL5700943 | 0.92 | ITGB1 (0.59) | ITGB1ITGA4ITGB7RORC | |
| SCHEMBL5700949 | 0.92 | ITGB1 (0.59) | ITGB1ITGA4ITGB7RORC | |
| SCHEMBL5700907 | 0.92 | ITGB1 (0.59) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5700900 | 0.88 | ITGB1 (0.70) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5700904 | 0.88 | ITGB1 (0.70) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5700912 | 0.87 | ITGB1 (0.55) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5700902 | 0.87 | ITGB1 (0.55) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5701042 | 0.85 | ITGB1 (0.53) | ITGB1ITGA4ITGB7RORC | |
| SCHEMBL5701040 | 0.85 | ITGB1 (0.53) | ITGB1ITGA4ITGB7RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |