Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700925 | 1.00 | MEN1 (0.60) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL27781112 | 0.90 | MEN1 (0.63) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL12226572 | 0.90 | MEN1 (0.63) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL14198862 | 0.90 | MEN1 (0.63) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL5700999 | 0.88 | MAPT (0.49) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL5701002 | 0.88 | MAPT (0.49) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL8173530 | 0.86 | MEN1 (0.60) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL5700886 | 0.85 | MEN1 (0.48) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL5700880 | 0.85 | MEN1 (0.48) | MEN1KMT2APOLBROCK2ROCK1 | |
| SCHEMBL7994713 | 0.84 | MEN1 (0.58) | MEN1KMT2APOLBROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |