Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702089 | 1.00 | NOTUM (0.49) | NOTUMTFPI2SMN1; SMN2ALDH1A1AGTR2 | |
| SCHEMBL432319 | 0.89 | SMN1; SMN2 (0.51) | NOTUMSMN1; SMN2ALDH1A1KMT2AOGFRL1 | |
| SCHEMBL630857 | 0.89 | SMN1; SMN2 (0.51) | NOTUMSMN1; SMN2ALDH1A1KMT2AOGFRL1 | |
| SCHEMBL15664724 | 0.89 | SMN1; SMN2 (0.51) | NOTUMSMN1; SMN2ALDH1A1KMT2AOGFRL1 | |
| SCHEMBL13603832 | 0.87 | SMN1; SMN2 (0.46) | NOTUMSMN1; SMN2ALDH1A1KMT2AOGFRL1 | |
| SCHEMBL8104378 | 0.87 | SMN1; SMN2 (0.46) | NOTUMSMN1; SMN2ALDH1A1KMT2AOGFRL1 | |
| Hydrochloric Acid SCHEMBL28132801 | 0.87 | SMN1; SMN2 (0.50) | NOTUMSMN1; SMN2ALDH1A1KMT2AOGFRL1 | |
| SCHEMBL9432301 | 0.84 | NOTUM (0.42) | NOTUMTFPI2SMN1; SMN2ALDH1A1AGTR2 | |
| SCHEMBL28221339 | 0.84 | NOTUM (0.54) | NOTUMSMN1; SMN2 | |
| SCHEMBL4770098 | 0.83 | NOTUM (0.38) | NOTUMTFPI2SMN1; SMN2ALDH1A1OGFRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974670-B1 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| US-6143554-A | Process for producing optically active n-substituted azetidine-2 carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0974670-A2 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |