Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.69 |
| ▸ | PPARD | Q03181 | 18/20 | 0.66 |
| ▸ | PPARG | P37231 | 16/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579458 | 0.87 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL5276147 | 0.85 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL5273484 | 0.83 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL5276321 | 0.83 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL5275997 | 0.83 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL5273452 | 0.83 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL14583362 | 0.82 | PPARA (1.00) | PPARAPPARDPPARG | |
| SCHEMBL5276145 | 0.82 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL2439016 | 0.81 | PPARA (0.81) | PPARAPPARDPPARG | |
| SCHEMBL2438126 | 0.81 | PPARA (0.81) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613326-B1 | (3-{3-'(2,4-BIS-TRIFLUORMETHYL-BENZYL)-(5-ETHYL-PYRIMIDIN-2-YL)-AMINO]-PROPOXY}-PHENYL)-ACETIC ACID AND RELATED COMPOUNDS AS MODULATORS OF PPARS AND METHODS OF TREATING METABOLIC DISORDERS | KALYPSYS INC (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20050070532-A1 | Aryl compounds as modulators of PPARS and methods of treating metabolic disorders | KALYPSYS, INC. | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070532-A1 | Aryl compounds as modulators of PPARS and methods of treating metabolic disorders | PPARG, PPARA, PPARD | PPARA 2/4885PPARD 3/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.