Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584438 | 0.87 | ADRB3 (0.49) | ADRB3ADRB1 | |
| SCHEMBL4584446 | 0.87 | ADRB3 (0.49) | ADRB3ADRB1 | |
| SCHEMBL4584178 | 0.81 | ADRB3 (0.53) | ADRB3ADRB1 | |
| SCHEMBL4584174 | 0.81 | ADRB3 (0.53) | ADRB3ADRB1 | |
| SCHEMBL5703671 | 0.74 | ADRB3 (0.49) | ADRB3ADRB1PDE4APDE4BPDE4C | |
| SCHEMBL5703670 | 0.74 | ADRB3 (0.51) | ADRB3ADRB1 | |
| SCHEMBL5704140 | 0.74 | ADRB3 (0.49) | ADRB3ADRB1PDE4APDE4BPDE4C | |
| SCHEMBL4584058 | 0.71 | ADRB3 (0.62) | ADRB3ADRB1 | |
| SCHEMBL4584057 | 0.71 | ADRB3 (0.62) | ADRB3ADRB1 | |
| SCHEMBL1622608 | 0.71 | ADRB3 (0.42) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697301-A2 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061433-A2 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |