Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | PPARD | Q03181 | 10/20 | 0.48 |
| ▸ | PPARA | Q07869 | 10/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615129 | 0.92 | PPARG (0.49) | PPARGPPARDPPARAFFAR1MEN1 | |
| SCHEMBL5704413 | 0.87 | PPARG (0.39) | PPARGPPARDPPARAFFAR1MEN1 | |
| SCHEMBL5704470 | 0.85 | PPARG (0.40) | PPARGPPARDPPARAFFAR1MEN1 | |
| SCHEMBL1745433 | 0.83 | FFAR1 (0.58) | PPARGPPARDPPARAFFAR1FFAR4 | |
| SCHEMBL4516207 | 0.83 | PPARG (0.45) | PPARGPPARDPPARAFFAR1MEN1 | |
| SCHEMBL4502925 | 0.82 | PPARG (0.49) | PPARGPPARDPPARAFFAR1MEN1 | |
| SCHEMBL4508283 | 0.82 | FFAR1 (0.56) | PPARGPPARDPPARAFFAR1MEN1 | |
| SCHEMBL4614607 | 0.81 | PPARG (0.40) | PPARGPPARDPPARAFFAR1MEN1 | |
| SCHEMBL4615683 | 0.81 | AKR1C3 (0.51) | PPARGPPARDPPARAMEN1KMT2A | |
| SCHEMBL4614422 | 0.81 | PPARG (0.42) | PPARGPPARDPPARAFFAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697304-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054176-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |