Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704588 | 1.00 | CETP (0.32) | CETP | |
| SCHEMBL5704598 | 1.00 | CETP (0.32) | CETP | |
| SCHEMBL5704659 | 1.00 | CETP (0.32) | CETP | |
| SCHEMBL12868483 | 1.00 | CETP (0.32) | CETP | |
| Hydrochloric Acid SCHEMBL19665892 | 0.97 | CETP (0.31) | CETP | |
| Hydrochloric Acid SCHEMBL7274888 | 0.97 | CETP (0.31) | CETP | |
| Trifluoroacetic Acid SCHEMBL3252839 | 0.87 | SLC7A5 (0.34) | — | |
| Trifluoroacetic Acid SCHEMBL3252844 | 0.87 | SLC7A5 (0.34) | — | |
| Cadaverine Tartrate SCHEMBL7319560 | 0.85 | TSHR (0.40) | — | |
| SCHEMBL16487147 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808097-A | OXIDATION OF THE CORRESPONDING HYDROXY COMPOUND | ZENECA LIMITED (GB) | 1998-09-15 | — | — | US | claimed |
| EP-0808327-A1 | PROLINE DERIVATIVES USEFUL AS INHIBITORS OF HUMAN LEUKOCYTE ELASTASE | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | claimed |
| WO-1996023812-A1 | PROLINE DERIVATIVES USEFUL AS INHIBITORS OF HUMAN LEUKOCYTE ELASTASE | ZENECA LIMITED (GB) | 1996-08-08 | — | — | WO | claimed |
| EP-1243576-B1 | PROCESSES FOR PRODUCING (AMINOMETHYL)TRIFLUOROMETHYLCARBINOL DERIVATIVES | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-10-11 | — | — | EP | disclosed |
| US-6646150-B1 | Reacting 1,3-oxazolidin-5-one derivative with trialkyl-(trifluoromethyl)silane; removing trialkylsilyl group; reductive decyclization | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| EP-1243576-A1 | PROCESSES FOR PRODUCING (AMINOMETHYL)TRIFLUOROCARBINOL DERIVATIVES | Dainippon Pharmaceutical Co., Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-6054593-A | Proline derivatives | ZENECA LIMITED (GB) | 2000-04-25 | — | — | US | disclosed |
| US-6048889-A | Proline derivatives | ZENECA LIMITED (GB) | 2000-04-11 | — | — | US | disclosed |
| US-5808097-A | OXIDATION OF THE CORRESPONDING HYDROXY COMPOUND | ZENECA LIMITED (GB) | 1998-09-15 | — | — | US | disclosed |
| EP-0808327-A1 | PROLINE DERIVATIVES USEFUL AS INHIBITORS OF HUMAN LEUKOCYTE ELASTASE | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| US-5686628-A | Proline derivatives | ZENECA LTD. (GB) | 1997-11-11 | — | — | US | disclosed |
| WO-1996023812-A1 | PROLINE DERIVATIVES USEFUL AS INHIBITORS OF HUMAN LEUKOCYTE ELASTASE | ZENECA LIMITED (GB) | 1996-08-08 | — | — | WO | disclosed |