⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13318151 | 0.74 | — | — | |
| SCHEMBL16019411 | 0.70 | — | — | |
| SCHEMBL17278419 | 0.70 | — | — | |
| SCHEMBL10343777 | 0.61 | — | — | |
| SCHEMBL3602470 | 0.57 | — | — | |
| SCHEMBL7288781 | 0.57 | — | — | |
| SCHEMBL4079948 | 0.57 | — | — | |
| SCHEMBL2039337 | 0.56 | — | — | |
| SCHEMBL1518887 | 0.55 | — | — | |
| SCHEMBL3675213 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853748-A | Trifluoromethyl-containing isoxazoline derivative, and preparation method and application thereof | 武汉工程大学 | 2022-08-05 | — | — | CN | claimed |
| EP-2809667-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2014-12-10 | — | — | EP | claimed |
| WO-2013116236-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS LLC (US) | 2013-08-08 | — | — | WO | claimed |
| EP-2601190-A1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | AH USA 42 LLC (US) | 2013-06-12 | — | — | EP | claimed |
| WO-2012017359-A1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-02-09 | — | — | WO | claimed |
| CN-121824444-A | Aryl amide compound containing trifluoromethyl isoxazoline, and preparation method and application thereof | 贵州大学 | 2026-04-10 | — | — | CN | disclosed |
| CN-121824444-A | Aryl amide compound containing trifluoromethyl isoxazoline, and preparation method and application thereof | 贵州大学 | 2026-04-10 | — | — | CN | disclosed |
| WO-2023037253-A1 | ISOXAZOLINE COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | PI INDUSTRIES LTD (IN) | 2023-03-16 | — | — | WO | disclosed |
| CN-114853748-A | Trifluoromethyl-containing isoxazoline derivative, and preparation method and application thereof | 武汉工程大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-114853748-A | Trifluoromethyl-containing isoxazoline derivative, and preparation method and application thereof | 武汉工程大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-110381738-A | Pesticide and Parasiticidal vinyl isoxazoline compound | 勃林格殷格翰动物保健美国公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-109561682-A | Pyridine compounds and their comprising isoxazoline ring and its purposes as herbicide | 牧牛研究所株式会社 | 2019-04-02 | — | — | CN | disclosed |
| EP-2809667-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | Zoetis LLC (US) | 2014-12-10 | — | — | EP | disclosed |
| WO-2013116236-A1 | PROCESS FOR THE PREPARATION OF CHIRAL ISOXAZOLINE AZETIDINE DERIVATIVES AS ANTIPARASITIC AGENTS | ZOETIS LLC (US) | 2013-08-08 | — | — | WO | disclosed |
| EP-2601190-A1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | AH USA 42 LLC (US) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017359-A1 | ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS | PFIZER INC. (US) | 2012-02-09 | — | — | WO | disclosed |
| US-4889551-A | Isoxazoline derivatives and plant growth regulators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1989-12-26 | — | — | US | disclosed |