Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113123 | 0.87 | CNR1 (0.60) | CNR1MAPTTP53MEN1KMT2A | |
| SCHEMBL4107145 | 0.87 | CNR1 (0.60) | CNR1MAPTTP53MEN1KMT2A | |
| SCHEMBL4107614 | 0.86 | CNR1 (0.71) | CNR1MAPTTP53POLBMEN1 | |
| SCHEMBL4112231 | 0.86 | CNR1 (0.59) | CNR1MAPTTP53POLBMEN1 | |
| SCHEMBL4116411 | 0.84 | CNR1 (0.54) | CNR1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4119717 | 0.82 | EPHX2 (0.57) | CNR1POLBMEN1KMT2AEPHX2 | |
| SCHEMBL4123912 | 0.81 | EPHX2 (0.61) | CNR1POLBMEN1KMT2AEPHX2 | |
| SCHEMBL4124304 | 0.81 | MEN1 (0.58) | CNR1POLBMEN1KMT2AEPHX2 | |
| SCHEMBL4115004 | 0.80 | CNR1 (0.59) | CNR1MAPTTP53POLBTSHR | |
| SCHEMBL4118060 | 0.77 | EPHX2 (0.59) | POLBMEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711175-A1 | DIUREA DERIVATIVES | Active Biotech AB (SE) | 2006-10-18 | — | — | EP | claimed |
| WO-2005074919-A1 | DIUREA DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | claimed |