Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | RHOC | P08134 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705917 | 0.92 | CNR1 (0.57) | CNR1MEN1KMT2AUTS2RMCHR1 | |
| SCHEMBL4117727 | 0.85 | CNR1 (0.60) | CNR1MEN1KMT2AUTS2RMCHR1 | |
| SCHEMBL4113873 | 0.84 | CNR1 (0.67) | CNR1MEN1KMT2AUTS2RMCHR1 | |
| SCHEMBL4117599 | 0.84 | CNR1 (0.67) | CNR1MEN1KMT2AUTS2RMCHR1 | |
| SCHEMBL4106129 | 0.83 | CNR1 (0.57) | CNR1MEN1KMT2AUTS2RMCHR1 | |
| SCHEMBL4119645 | 0.83 | MCHR1 (0.60) | CNR1MEN1KMT2AUTS2RMCHR1 | |
| SCHEMBL4112236 | 0.82 | CNR1 (0.56) | CNR1MEN1KMT2AUTS2RMCHR1 | |
| SCHEMBL4118998 | 0.80 | CNR1 (0.61) | CNR1MEN1KMT2AUTS2RGAA | |
| SCHEMBL4112186 | 0.79 | MEN1 (0.60) | CNR1MEN1KMT2AUTS2RMCHR1 | |
| SCHEMBL4107145 | 0.79 | CNR1 (0.60) | CNR1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711175-A1 | DIUREA DERIVATIVES | Active Biotech AB (SE) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005074919-A1 | DIUREA DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |