Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4107405 | 0.85 | MCHR1 (0.60) | MCHR1MEN1KMT2ANOX1NPC1 | |
| SCHEMBL4107371 | 0.85 | EPHX2 (0.45) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL4120523 | 0.83 | MCHR1 (0.53) | MCHR1MEN1KMT2ANOX1NPC1 | |
| SCHEMBL4113680 | 0.82 | MCHR1 (0.54) | MCHR1MEN1KMT2AALDH1A1MTOR | |
| SCHEMBL4118376 | 0.79 | MCHR1 (0.66) | MCHR1MEN1KMT2AALDH1A1THRB | |
| SCHEMBL4118355 | 0.77 | MEN1 (0.55) | MCHR1MEN1KMT2ANOX1NPC1 | |
| SCHEMBL4114249 | 0.76 | MCHR1 (0.59) | MCHR1MEN1KMT2ANOX1NPC1 | |
| SCHEMBL4115328 | 0.75 | MCHR1 (0.61) | MCHR1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL4119645 | 0.74 | MCHR1 (0.60) | MCHR1MEN1KMT2AMAPTGAA | |
| SCHEMBL4124390 | 0.74 | MCHR1 (0.54) | MCHR1MEN1KMT2AALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711175-A1 | DIUREA DERIVATIVES | Active Biotech AB (SE) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005074919-A1 | DIUREA DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |