Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CDK9 | P50750 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634 | 0.97 | EPHX2 (0.70) | EPHX2TP53EPHX1TSHRCDK9 | |
| Benzene SCHEMBL28162617 | 0.97 | EPHX2 (0.70) | EPHX2TP53EPHX1TSHRCDK9 | |
| Hydrochloric Acid SCHEMBL9156069 | 0.94 | EPHX2 (0.67) | EPHX2TP53EPHX1TSHRCDK9 | |
| Fluoride SCHEMBL10885265 | 0.94 | EPHX2 (0.67) | EPHX2TP53EPHX1TSHRCDK9 | |
| Ammonia Solution, Strong SCHEMBL28135860 | 0.94 | EPHX2 (0.67) | EPHX2TP53EPHX1TSHRCDK9 | |
| Water SCHEMBL9215020 | 0.94 | EPHX2 (0.67) | EPHX2TP53EPHX1TSHRCDK9 | |
| SCHEMBL11353365 | 0.94 | EPHX2 (0.67) | EPHX2TP53EPHX1TSHRCDK9 | |
| Bromide SCHEMBL5706299 | 0.94 | EPHX2 (0.67) | EPHX2TP53EPHX1TSHRCDK9 | |
| Water SCHEMBL9215017 | 0.94 | EPHX2 (0.67) | EPHX2TP53EPHX1TSHRCDK9 | |
| SCHEMBL27617033 | 0.94 | EPHX2 (0.67) | EPHX2TP53EPHX1TSHRCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697313-B1 | PROCESSES FOR THE PREPARATION OF AMINOALKYL PHENYLCARBAMATES | GENERICS UK LTD (GB) | 2015-09-16 | — | — | EP | disclosed |
| EP-1697313-A2 | PROCESSES FOR THE PREPARATION OF AMINOALKYL PHENYLCARBAMATES | Merck Generics (UK) Limited (GB) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061446-A2 | PROCESSES FOR THE PREPARATION OF AMINOALKYL PHENYLCARBAMATES | GENERICS [UK] LIMITED (GB) | 2005-07-07 | — | — | WO | disclosed |