SCHEMBL5707173

SCHEMBL5707173

COC(=O)CC=NCCN=CCC(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
GAA P10253 3/20 0.39
HSD17B10 Q99714 2/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
POLB P06746 1/20 0.36
ALPI P09923 1/20 0.36
ALPG P10696 1/20 0.36
PKM P14618 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA12 O43570 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
LMNA P02545 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17783198 1.00 TSHR (0.42) TSHRGAAHSD17B10MGAMSI
SCHEMBL15752651 0.87 TSHR (0.36) TSHRGAAHSD17B10MGAMSI
SCHEMBL10409893 0.82 POLB (0.45) POLBCA12CA14EPHX2
SCHEMBL18862923 0.78
Propionic Acid SCHEMBL25217288 0.77 POLB (0.41) TSHRHSD17B10KMT2AMEN1POLB
Propionic Acid SCHEMBL25253832 0.77 POLB (0.41) TSHRHSD17B10KMT2AMEN1POLB
Propionic Acid SCHEMBL25216494 0.77 POLB (0.41) TSHRHSD17B10KMT2AMEN1POLB
Propionic Acid SCHEMBL25215716 0.77 POLB (0.41) TSHRHSD17B10KMT2AMEN1POLB
Propionic Acid SCHEMBL25218017 0.77 POLB (0.41) TSHRHSD17B10KMT2AMEN1POLB
Propionic Acid SCHEMBL25217289 0.77 POLB (0.41) TSHRHSD17B10KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3020766-B1 CURING ACCELERATOR FOR OXIDATION POLYMERIZED UNSATURATED RESIN, PRINTING INK, AND COATING MATERIAL DAINIPPON INK & CHEMICALS (JP) 2019-11-20 EP disclosed
US-9896603-B2 Curing accelerator for oxidative polymerization-type unsaturated resin, printing ink, and coating material DIC CORPORATION (JP) 2018-02-20 US disclosed
US-20160152867-A1 CURING ACCELERATOR FOR OXIDATIVE POLYMERIZATION-TYPE UNSATURATED RESIN, PRINTING INK, AND COATING MATERIAL DIC CORPORATION (JP) 2016-06-02 US disclosed
EP-3020766-A1 CURING ACCELERATOR FOR OXIDATION POLYMERIZED UNSATURATED RESIN, PRINTING INK, AND COATING MATERIAL DIC Corporation (JP) 2016-05-18 EP disclosed
EP-1114836-B1 PROCESS FOR PRODUCING A RESIN COMPOSITION NAT INST OF ADVANCED IND SCIEN (JP) 2006-11-08 EP disclosed
US-6344516-B1 TRANSITION METAL COMPLEX CATALYST, OXIDATATIVE POLYMERIZATION OF PHENOL-CONTAINING VEGETABLE OIL NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2002-02-05 US disclosed
EP-1114836-A1 RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME Japan as represented by Secretary of Agency of Industrial Science and Technology (JP) 2001-07-11 EP disclosed