Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913640 | 0.93 | CSF1R (0.52) | CSF1R | |
| SCHEMBL4905217 | 0.92 | CSF1R (0.59) | CSF1R | |
| SCHEMBL4905433 | 0.88 | CSF1R (0.52) | CSF1R | |
| SCHEMBL4918243 | 0.86 | CSF1R (0.59) | CSF1R | |
| SCHEMBL4910491 | 0.86 | CSF1R (0.59) | CSF1R | |
| SCHEMBL4913890 | 0.84 | CSF1R (0.52) | CSF1R | |
| SCHEMBL4907869 | 0.83 | CSF1R (0.64) | CSF1R | |
| SCHEMBL4915409 | 0.83 | CSF1R (0.53) | CSF1R | |
| SCHEMBL27682428 | 0.82 | CSF1R (0.54) | CSF1R | |
| SCHEMBL4905307 | 0.82 | CSF1R (0.53) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718615-A1 | NOVEL QUINOLINE-CARBAXAMIDES AS JACK3 KINASE MODULATORS | AstraZeneca AB (SE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005075429-A1 | NOVEL QUINOLINE-CARBAXAMIDES AS JACK3 KINASE MODULATORS | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | WO | disclosed |