Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 3/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5707957 | 0.99 | KDM4E (0.51) | KDM4EMAPTGAAGFERRAD52 | |
| SCHEMBL5707955 | 0.94 | MAPT (0.58) | KDM4EMAPTGAAGFERRAD52 | |
| Hydrochloric Acid SCHEMBL5707951 | 0.93 | MAPT (0.57) | KDM4EMAPTGAAGFERRAD52 | |
| SCHEMBL5707929 | 0.92 | MAPT (0.55) | KDM4EMAPTGAAGFERRAD52 | |
| Hydrochloric Acid SCHEMBL5707968 | 0.90 | MAPT (0.54) | KDM4EMAPTGAAGFERRAD52 | |
| SCHEMBL5203955 | 0.85 | MAPT (0.59) | KDM4EMAPTGAAGFERRAD52 | |
| Hydrochloric Acid SCHEMBL5364971 | 0.84 | MAPT (0.62) | KDM4EMAPTGAAGFERRAD52 | |
| Hydrochloric Acid SCHEMBL6418329 | 0.84 | MAPT (0.60) | KDM4EMAPTGAAGFERRAD52 | |
| SCHEMBL5707908 | 0.83 | GAA (0.58) | KDM4EMAPTGAARAD52ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5707937 | 0.82 | GAA (0.56) | KDM4EMAPTGAARAD52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462445-B1 | Paraphenyldiamine derivatives concisting of a cyclic diaza group substituted by a cationic radical and use of these derivatives for dyeing keratin fibres | OREAL (FR) | 2006-10-18 | — | — | EP | claimed |
| EP-1462445-B1 | Paraphenyldiamine derivatives concisting of a cyclic diaza group substituted by a cationic radical and use of these derivatives for dyeing keratin fibres | OREAL (FR) | 2006-10-18 | — | — | EP | disclosed |