Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763589 | 0.83 | HTR2C (0.47) | NPC1CYP2C19ALDH1A1HTR2C | |
| SCHEMBL7468424 | 0.83 | HTR2C (0.47) | NPC1CYP2C19ALDH1A1HTR2C | |
| SCHEMBL2339025 | 0.81 | PPARG (0.41) | TSHRCYP3A4CYP2C19ALDH1A1BCHE | |
| SCHEMBL2361551 | 0.81 | MDM2 (0.34) | TSHRALDH1A1MDM2HTR2C | |
| SCHEMBL7970669 | 0.79 | HTR2C (0.43) | NPC1ALDH1A1HTR2C | |
| SCHEMBL7668068 | 0.78 | ABCB1 (0.42) | BCHEKDM1AKDM4E | |
| SCHEMBL7489317 | 0.78 | ABCB1 (0.42) | BCHEKDM1AKDM4E | |
| SCHEMBL16237602 | 0.78 | ABCB1 (0.42) | BCHEKDM1AKDM4E | |
| SCHEMBL286796 | 0.78 | ABCB1 (0.42) | BCHEKDM1AKDM4E | |
| SCHEMBL7489323 | 0.78 | ABCB1 (0.42) | BCHEKDM1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370541-B1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | DABUR INDIA LTD (IN) | 2006-11-02 | — | — | EP | disclosed |
| EP-1370541-A1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | Dabur India Limited (IN) | 2003-12-17 | — | — | EP | disclosed |
| US-20030013888-A1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | DABUR PHARMA LIMITED (IN) | 2003-01-16 | — | — | US | disclosed |
| US-6506905-B1 | Taxol intermediates | DABUR INDIA LIMITED (IN) | 2003-01-14 | — | — | US | disclosed |
| WO-2002066448-A1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | DABUR INDIA LIMITED (IN) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013888-A1 | METHOD OF PREPARATION OF PACLITAXEL (TAXOL) USING 3-(ALK-2-YNYLOXY) CARBONYL-5-OXAZOLIDINE CARBOXYLIC ACID | ALK, AHR, PDGFRA | NPC1 3025/4885TSHR 1022/4885CYP1A2 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.