Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.46 |
| ▸ | PPARD | Q03181 | 10/20 | 0.46 |
| ▸ | PPARG | P37231 | 14/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708251 | 0.92 | PPARD (0.46) | PPARAPPARDPPARG | |
| SCHEMBL3965838 | 0.91 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL3969652 | 0.84 | PPARD (0.51) | PPARAPPARDPPARG | |
| SCHEMBL3964471 | 0.82 | PPARD (0.52) | PPARAPPARDPPARG | |
| SCHEMBL3961082 | 0.80 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL5708202 | 0.79 | PARP1 (0.40) | PPARAPPARDPPARGADORA3 | |
| SCHEMBL3960605 | 0.77 | PPARA (0.46) | PPARAPPARDPPARG | |
| SCHEMBL3960962 | 0.75 | PPARD (0.56) | PPARAPPARDPPARG | |
| SCHEMBL6034478 | 0.75 | PPARA (0.41) | PPARAPPARDPPARG | |
| SCHEMBL5708226 | 0.74 | PPARA (0.59) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706386-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-10-04 | — | — | EP | claimed |
| WO-2005066136-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-07-21 | — | — | WO | claimed |