Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.41 |
| ▸ | PPARA | Q07869 | 9/20 | 0.41 |
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961112 | 0.92 | PPARD (0.41) | PPARDPPARAPPARGPARP1FFAR1 | |
| SCHEMBL3964310 | 0.88 | PPARD (0.52) | PPARDPPARAPPARG | |
| SCHEMBL5708221 | 0.85 | PPARD (0.40) | PPARDPPARAPPARGPARP1 | |
| SCHEMBL3965842 | 0.85 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL3964607 | 0.85 | PPARD (0.41) | PPARDPPARAPPARGPARP1FFAR1 | |
| SCHEMBL5708243 | 0.84 | PPARD (0.40) | PPARDPPARAPPARGPARP1FFAR1 | |
| SCHEMBL5708218 | 0.83 | PPARD (0.39) | PPARDPPARAPPARG | |
| SCHEMBL3960614 | 0.83 | PPARD (0.56) | PPARDPPARAPPARGFFAR1FFAR4 | |
| SCHEMBL3962003 | 0.82 | PPARD (0.43) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL3964651 | 0.81 | PPARD (0.40) | PPARDPPARAPPARGFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706386-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-10-04 | — | — | EP | claimed |
| WO-2005066136-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-07-21 | — | — | WO | claimed |