Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.47 |
| ▸ | PPARD | Q03181 | 17/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964493 | 0.91 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL5708235 | 0.89 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL3964296 | 0.85 | PPARA (0.50) | PPARAPPARDPPARG | |
| SCHEMBL3964759 | 0.85 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL4183667 | 0.84 | PPARA (0.48) | PPARAPPARDPPARG | |
| SCHEMBL3968731 | 0.84 | PPARD (0.39) | PPARAPPARDPPARG | |
| SCHEMBL5708226 | 0.82 | PPARA (0.59) | PPARAPPARDPPARG | |
| SCHEMBL3961082 | 0.81 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL3966965 | 0.81 | PPARD (0.57) | PPARAPPARDPPARG | |
| SCHEMBL5708244 | 0.80 | PPARA (0.41) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706386-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-10-04 | — | — | EP | claimed |
| WO-2005066136-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-07-21 | — | — | WO | claimed |