Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 15/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961095 | 0.87 | PPARD (0.55) | PPARDPPARA | |
| SCHEMBL3965058 | 0.86 | PPARD (0.46) | TRPV1PPARDPPARA | |
| SCHEMBL3964640 | 0.85 | TRPV1 (0.44) | TRPV1PPARDPPARGPPARA | |
| SCHEMBL4792460 | 0.83 | PPARD (0.42) | PPARDPPARGPPARA | |
| SCHEMBL3964879 | 0.79 | TRPV1 (0.42) | TRPV1PPARDPPARGPPARA | |
| SCHEMBL3965580 | 0.78 | PPARD (0.45) | TRPV1PPARDPPARA | |
| SCHEMBL3964385 | 0.76 | PPARD (0.46) | TRPV1PPARDPPARGPPARA | |
| SCHEMBL3964305 | 0.73 | PPARD (0.55) | PPARDPPARA | |
| SCHEMBL3966218 | 0.73 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL4792890 | 0.72 | PTPN1 (0.40) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1706386-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-10-04 | — | — | EP | claimed |
| WO-2005066136-A1 | BICYCLIC DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-07-21 | — | — | WO | claimed |