Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570867 | 0.82 | BACE1 (0.51) | BACE1 | |
| SCHEMBL570770 | 0.82 | BACE1 (0.51) | BACE1 | |
| SCHEMBL570684 | 0.82 | BACE1 (0.51) | BACE1 | |
| SCHEMBL10285177 | 0.80 | BACE1 (0.37) | BACE1CTSD | |
| SCHEMBL10285131 | 0.80 | BACE1 (0.37) | BACE1CTSD | |
| SCHEMBL10285126 | 0.80 | BACE1 (0.37) | BACE1CTSD | |
| SCHEMBL570381 | 0.79 | — | — | |
| SCHEMBL570901 | 0.79 | — | — | |
| Trifluoroacetic Acid SCHEMBL15063416 | 0.74 | BACE1 (0.36) | BACE1CTSD | |
| SCHEMBL2371316 | 0.72 | BACE1 (0.39) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601197-A1 | AMINO-ISO-INDOLE, AMINO-AZA-ISO-INDOLE, AMINO-DIHYDROISOQUINOLINE AND AMINO-BENZOXAZINE COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | Amgen Inc. (US) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012019056-A1 | AMINO-ISO-INDOLE, AMINO-AZA-ISO-INDOLE, AMINO-DIHYDROISOQUINOLINE AND AMINO-BENZOXAZINE COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | AMGEN INC. (US) | 2012-02-09 | — | — | WO | disclosed |