SCHEMBL5708703

SCHEMBL5708703

CCCC(CC)(CCCCl)CO[SiH3]

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8376028 0.90 TSHR (0.31) TSHRTDP1
SCHEMBL3482714 0.86
SCHEMBL3482178 0.85
SCHEMBL3481475 0.81
SCHEMBL1143925 0.81
SCHEMBL3482417 0.77
SCHEMBL3481917 0.77
SCHEMBL3482565 0.77
SCHEMBL4082635 0.77
SCHEMBL415768 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423858-B1 REACTING ORGANOSILANE WITH AMMONIA OR ORGANIC AMINE COMPOUND, EVAPORATING AMMONIA OR ORGANIC AMINE UNDER REDUCED PRESSURE, ALLOWING AMMONIUM CHLORIDE OR AMINOHYDROCHLORIDE BY-PRODUCTS TO CRYSTALLIZE AND SEPARATE, DISTILLING PRODUCT DEGUSSA AG (DE) 2002-07-23 US claimed
US-20020065428-A1 MANUFACTURING PROCESS FOR AMINOALKYL SILANES DEGUSSA AG (DE) 2002-05-30 US claimed
EP-1295889-B1 Process for preparing aminoalkylsilanes DEGUSSA (DE) 2006-10-11 EP disclosed
EP-1209162-B1 Process for preparing amino alkyl silanes DEGUSSA (DE) 2005-12-28 EP disclosed
EP-1295889-A2 Process for preparing aminoalkylsilanes Degussa AG (DE) 2003-03-26 EP disclosed
US-6423858-B1 REACTING ORGANOSILANE WITH AMMONIA OR ORGANIC AMINE COMPOUND, EVAPORATING AMMONIA OR ORGANIC AMINE UNDER REDUCED PRESSURE, ALLOWING AMMONIUM CHLORIDE OR AMINOHYDROCHLORIDE BY-PRODUCTS TO CRYSTALLIZE AND SEPARATE, DISTILLING PRODUCT DEGUSSA AG (DE) 2002-07-23 US disclosed
US-20020065428-A1 MANUFACTURING PROCESS FOR AMINOALKYL SILANES DEGUSSA AG (DE) 2002-05-30 US disclosed
EP-1209162-A2 Process for preparing amino alkyl silanes Degussa AG (DE) 2002-05-29 EP disclosed