Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500718 | 0.97 | — | — | |
| SCHEMBL25600194 | 0.97 | — | — | |
| SCHEMBL6907462 | 0.97 | — | — | |
| SCHEMBL29616471 | 0.97 | — | — | |
| SCHEMBL7123594 | 0.97 | — | — | |
| SCHEMBL8498697 | 0.97 | — | — | |
| SCHEMBL29309526 | 0.97 | — | — | |
| SCHEMBL784551 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2CA14CA12ALDH1A1KMT2A | |
| SCHEMBL13946795 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2CA14CA12ALDH1A1KMT2A | |
| SCHEMBL28661109 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2CA14CA12ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727533-A1 | USE OF CYSTEINYL LEUKOTRIENE 2 RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005082346-A1 | USE OF CYSTEINYL LEUKOTRIENE 2 RECEPTOR ANTAGONISTS | MERCK & CO, INC. (US) | 2005-09-09 | — | — | WO | disclosed |