SCHEMBL5709934

SCHEMBL5709934

Nc1nc2c(ncn2[C@H]2C[C@H](OP(=O)(O)O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.66
P2RY1 P47900 1/20 0.63
NT5E P21589 1/20 0.56
P2RY2 P41231 1/20 0.56
P2RY4 P51582 1/20 0.56
P2RY6 Q15077 1/20 0.56
FUT5 Q11128 1/20 0.54
TGM2 P21980 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17586738 1.00 POLB (0.66) POLBP2RY1NT5EP2RY2P2RY4
SCHEMBL24059912 1.00 POLB (0.66) POLBP2RY1NT5EP2RY2P2RY4
SCHEMBL20277594 1.00 POLB (0.66) POLBP2RY1NT5EP2RY2P2RY4
SCHEMBL12714668 0.93 POLB (0.67) POLBP2RY1NT5EP2RY2P2RY4
SCHEMBL12714691 0.92 POLB (0.71) POLBP2RY1NT5EP2RY2P2RY4
SCHEMBL18107896 0.92 POLB (0.61) POLBP2RY1NT5EP2RY2P2RY4
SCHEMBL24465144 0.92 POLB (0.65) POLBP2RY1NT5EP2RY2P2RY4
SCHEMBL13134473 0.92 POLB (0.65) POLBP2RY1NT5EP2RY2P2RY4
SCHEMBL1971037 0.92 POLB (0.62) POLBP2RY1NT5EP2RY2P2RY4
SCHEMBL1971043 0.92 POLB (0.62) POLBP2RY1NT5EP2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024239431-A1 METHOD FOR PHOSPHORYLATION OF NUCLEIC ACID AT 3' END AND LIBRARY CONSTRUCTION 深圳华大智造科技股份有限公司 2024-11-28 WO claimed
US-11185100-B2 Methods for modulating taste receptors MARS, INCORPORATED (US) 2021-11-30 US claimed
EP-3122756-A1 INORGANIC-ORGANIC HYBRID COMPOUND Karlsruher Institut für Technologie (DE) 2017-02-01 EP claimed
WO-2015144282-A1 INORGANIC-ORGANIC HYBRID COMPOUND Karlsruher Institut für Technologie (DE) 2015-10-01 WO claimed
EP-1907590-B1 T7 RNA POLYMERASE AND METHODS FOR THE GENERATION OF FULLY 2'-MODIFIED NUCLEIC ACID TRANSCRIPTS ARCHEMIX LLC (US) 2012-09-19 EP claimed
WO-2024239431-A1 METHOD FOR PHOSPHORYLATION OF NUCLEIC ACID AT 3' END AND LIBRARY CONSTRUCTION 深圳华大智造科技股份有限公司 2024-11-28 WO disclosed
EP-4403042-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2024-07-24 EP disclosed
EP-3229612-B1 USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2024-06-26 EP disclosed
CN-117137048-A Flavor composition, food comprising the same, and method for increasing the flavor intensity of the umami taste of food 马斯公司 2023-12-01 CN disclosed
US-11185100-B2 Methods for modulating taste receptors MARS, INCORPORATED (US) 2021-11-30 US disclosed
EP-3229610-B1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2021-06-09 EP disclosed
US-20190021380-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2019-01-24 US disclosed
US-20180255813-A1 METHODS FOR MODULATING TASTE RECEPTORS MARS, INCORPORATED (US) 2018-09-13 US disclosed
US-20180168208-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2018-06-21 US disclosed
EP-3122756-A1 INORGANIC-ORGANIC HYBRID COMPOUND Karlsruher Institut für Technologie (DE) 2017-02-01 EP disclosed
WO-2015144282-A1 INORGANIC-ORGANIC HYBRID COMPOUND Karlsruher Institut für Technologie (DE) 2015-10-01 WO disclosed
EP-1720976-B1 METHOD AND DEVICE FOR THERMAL CONDITIONING OF A CELL INSILICO BIOTECHNOLOGY AG (DE) 2014-10-08 EP disclosed
EP-1720976-A1 METHOD AND DEVICE FOR THERMAL CONDITIONING OF A CELL Insilico Biotechnology Gmbh (DE) 2006-11-15 EP disclosed
WO-2005083054-A1 METHOD AND DEVICE FOR THERMAL CONDITIONING OF A CELL INSILICO BIOTECHNOLOGY GMBH (DE) 2005-09-09 WO disclosed