Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31544881 | 0.83 | TYR (0.53) | TP53CYP3A4TYRHTTMEN1 | |
| SCHEMBL5142259 | 0.82 | TP53 (0.44) | TP53CYP3A4TYRHTTMEN1 | |
| SCHEMBL10938970 | 0.82 | TP53 (0.44) | TP53CYP3A4TYRHTTMEN1 | |
| SCHEMBL31545402 | 0.81 | TYR (0.50) | TP53CYP3A4TYRHTTMEN1 | |
| SCHEMBL5709904 | 0.81 | TYR (0.46) | TP53CYP3A4TYRHTTMEN1 | |
| SCHEMBL5709921 | 0.81 | ESR1 (0.47) | TP53CYP3A4TYRHTTMEN1 | |
| SCHEMBL10945234 | 0.80 | ESR1 (0.42) | TP53CYP3A4TYRHTTMEN1 | |
| SCHEMBL11220839 | 0.79 | TYR (0.38) | CYP3A4TYRMAPTALOX15TSHR | |
| SCHEMBL11092453 | 0.78 | CYSLTR2 (0.43) | TP53CYP3A4TYRHTTMEN1 | |
| SCHEMBL9424107 | 0.76 | CYSLTR2 (0.39) | TP53CYP3A4TYRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6946168-B2 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. (JP) | 2005-09-20 | — | — | US | disclosed |
| US-20040077743-A1 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. | 2004-04-22 | — | — | US | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1179435-A1 | Reversible thermochromic composition having improved light-fastness and product comprising same | The Pilot Ink Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |