Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11013342 | 0.86 | ESR2 (0.44) | CA2CA1ESR2TSHRHSD17B10 | |
| SCHEMBL1597822 | 0.86 | ESR2 (0.47) | CA2CA1ESR2TSHRHSD17B10 | |
| SCHEMBL28315036 | 0.85 | TDP1 (0.44) | HTR1ATSHRHSD17B10CYP3A4ALDH1A1 | |
| SCHEMBL8821813 | 0.84 | CA1 (0.39) | CA2CA1ESR2HTR1ATSHR | |
| SCHEMBL30343452 | 0.82 | ESR2 (0.50) | CA2CA1ESR2TSHRHSD17B10 | |
| SCHEMBL1595522 | 0.82 | ESR2 (0.50) | CA2CA1ESR2TSHRHSD17B10 | |
| SCHEMBL20520242 | 0.82 | ESR1 (0.47) | ESR2HTR1AKAT8 | |
| SCHEMBL20520204 | 0.82 | ESR1 (0.47) | ESR2HTR1AKAT8 | |
| SCHEMBL20520233 | 0.82 | ESR1 (0.47) | ESR2HTR1AKAT8 | |
| SCHEMBL20520274 | 0.82 | ESR1 (0.47) | ESR2HTR1AKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732896-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | Aventis Pharmaceuticals Inc. (US) | 2006-12-20 | — | — | EP | disclosed |
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005097750-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-6946168-B2 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. (JP) | 2005-09-20 | — | — | US | disclosed |
| US-20040077743-A1 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. | 2004-04-22 | — | — | US | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1179435-A1 | Reversible thermochromic composition having improved light-fastness and product comprising same | The Pilot Ink Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |