Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.40 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820578 | 0.87 | TOP1 (0.44) | SOAT2ACAT1SOAT1ESR1TYR | |
| SCHEMBL12339853 | 0.86 | ESR1 (0.36) | SOAT2ACAT1SOAT1ESR1TP53 | |
| SCHEMBL11706703 | 0.84 | MEN1 (0.34) | TP53CYP2D6CYP2C9ALOX15CYP2C19 | |
| SCHEMBL12339845 | 0.84 | TP53 (0.35) | SOAT2ACAT1SOAT1ESR1TP53 | |
| SCHEMBL11234390 | 0.80 | ESR1 (0.39) | ESR1TP53CYP2D6CYP2C9ALOX15 | |
| SCHEMBL14493473 | 0.80 | ESR1 (0.39) | ESR1TP53CYP2D6CYP2C9ALOX15 | |
| SCHEMBL11451555 | 0.80 | ESR1 (0.39) | ESR1TP53CYP2D6CYP2C9ALOX15 | |
| SCHEMBL12339842 | 0.79 | TP53 (0.36) | SOAT2ACAT1SOAT1ESR1TP53 | |
| SCHEMBL28237571 | 0.78 | ESR1 (0.38) | SOAT2ACAT1SOAT1ESR1TP53 | |
| SCHEMBL224494 | 0.78 | CYP2D6 (0.51) | ESR1TP53CYP2D6CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6946168-B2 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. (JP) | 2005-09-20 | — | — | US | disclosed |
| US-20040077743-A1 | Photochromic phthalein dyes encapsulated in curable oligomers used as coatings on geometric shaped suports as designs | THE PILOT INK CO., LTD. | 2004-04-22 | — | — | US | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1179435-A1 | Reversible thermochromic composition having improved light-fastness and product comprising same | The Pilot Ink Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |