SCHEMBL5710328

SCHEMBL5710328

Ic1ccc(O[C@H]2CN3CCC2CC3)cc1.O[C@H]1CN2CCC1CC2

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LSS P48449 1/20 0.53
CHRNA7 P36544 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706609 1.00 LSS (0.53) LSSCHRNA7
SCHEMBL5710323 1.00 LSS (0.53) LSSCHRNA7
SCHEMBL31507154 0.91 LSS (0.57) LSSCHRNA7
SCHEMBL5420231 0.91 LSS (0.57) LSSCHRNA7
SCHEMBL1018942 0.91 LSS (0.57) LSSCHRNA7
Hydrochloric Acid SCHEMBL5649595 0.90 LSS (0.56) LSSCHRNA7
SCHEMBL5407098 0.87 LSS (0.53) LSSCHRNA7
SCHEMBL5418233 0.87 LSS (0.53) LSSCHRNA7
SCHEMBL5710504 0.86 LSS (0.53) LSSCHRNA7
Hydrochloric Acid SCHEMBL5652369 0.85 LSS (0.52) LSSCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1735305-A2 3-QUINUCLIDINYL HETEROATOM BRIDGED BIARYL DERIVATIVES ABBOTT LABORATORIES (US) 2006-12-27 EP disclosed
WO-2005066167-A2 3-QUINUCLIDINYL HETEROATOM BRIDGED BIARYL DERIVATIVES ABBOTT LABORATORIES (US) 2005-07-21 WO disclosed