Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710394 | 1.00 | LSS (0.51) | LSSCHRNA7BCHEACHECHRM2 | |
| SCHEMBL5710396 | 1.00 | LSS (0.51) | LSSCHRNA7BCHEACHECHRM2 | |
| SCHEMBL5710516 | 1.00 | LSS (0.51) | LSSCHRNA7BCHEACHECHRM2 | |
| SCHEMBL5710514 | 1.00 | LSS (0.51) | LSSCHRNA7BCHEACHECHRM2 | |
| SCHEMBL5390767 | 0.92 | LSS (0.55) | LSSCHRNA7BCHEACHECHRM2 | |
| SCHEMBL5403372 | 0.92 | LSS (0.55) | LSSCHRNA7BCHEACHECHRM2 | |
| SCHEMBL5396813 | 0.92 | LSS (0.55) | LSSCHRNA7BCHEACHECHRM2 | |
| SCHEMBL5710541 | 0.91 | LSS (0.43) | LSSCHRNA7BCHEACHECHRM2 | |
| Hydrochloric Acid SCHEMBL5652765 | 0.90 | LSS (0.53) | LSSCHRNA7BCHEACHECHRM2 | |
| Hydrochloric Acid SCHEMBL5653334 | 0.90 | LSS (0.53) | LSSCHRNA7BCHEACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735305-A2 | 3-QUINUCLIDINYL HETEROATOM BRIDGED BIARYL DERIVATIVES | ABBOTT LABORATORIES (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005066167-A2 | 3-QUINUCLIDINYL HETEROATOM BRIDGED BIARYL DERIVATIVES | ABBOTT LABORATORIES (US) | 2005-07-21 | — | — | WO | disclosed |