Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.77 |
| ▸ | BCL2 | P10415 | 18/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571226 | 0.93 | BCL2L1 (0.75) | BCL2L1BCL2 | |
| SCHEMBL570847 | 0.93 | BCL2L1 (0.75) | BCL2L1BCL2 | |
| SCHEMBL571105 | 0.88 | BCL2L1 (0.73) | BCL2L1BCL2 | |
| SCHEMBL554648 | 0.87 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL554071 | 0.87 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL554782 | 0.87 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL554070 | 0.87 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL553692 | 0.85 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL554672 | 0.85 | BCL2L1 (1.00) | BCL2L1BCL2 | |
| SCHEMBL553691 | 0.85 | BCL2L1 (1.00) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601177-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | AstraZeneca AB (SE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017251-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | WO | disclosed |